Predicting Causal Relationships from Biological Data: Applying Automated Causal Discovery on Mass Cytometry Data of Human Immune Cells

Abstract Learning the causal relationships that define a molecular system allows us to predict how the system will respond to different interventions. Distinguishing causality from mere association typically requires randomized experiments. Methods for automated  causal discovery from limited experi...

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Bibliographic Details
Main Authors: Sofia Triantafillou, Vincenzo Lagani, Christina Heinze-Deml, Angelika Schmidt, Jesper Tegner, Ioannis Tsamardinos
Format: Article
Language:English
Published: Nature Portfolio 2017-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-08582-x