Inducible nitric oxide synthase inhibitor, 1400W, mitigates DFP-induced long-term neurotoxicity in the rat model

Inducible nitric oxide synthase inhibitor, 1400W, mitigates DFP-induced long-term neurotoxicity in the rat model

Chemical nerve agents (CNA) are increasingly becoming a threat to both civilians and military personnel. CNA-induced acute effects on the nervous system have been known for some time and the long-term consequences are beginning to emerge. In this study, we used diisopropylfluorophosphate (DFP), a se...

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Bibliographic Details
Main Authors: Marson Putra, Shaunik Sharma, Meghan Gage, Grace Gasser, Andy Hinojo-Perez, Ashley Olson, Adriana Gregory-Flores, Sreekanth Puttachary, Chong Wang, Vellareddy Anantharam, Thimmasettappa Thippeswamy
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Neurobiology of Disease
Subjects:
Neuroinflammation
Video-EEG
Neurodegeneration
Spontaneous recurrent seizure
Chemical nerve agent
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996119300828

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http://www.sciencedirect.com/science/article/pii/S0969996119300828

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