Analysis of heterogeneity in T2-weighted MR images can differentiate pseudoprogression from progression in glioblastoma.

To develop an image analysis technique that distinguishes pseudoprogression from true progression by analyzing tumour heterogeneity in T2-weighted images using topological descriptors of image heterogeneity called Minkowski functionals (MFs).Using a retrospective patient cohort (n = 50), and blinded...

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Bibliographic Details
Main Authors: Thomas C Booth, Timothy J Larkin, Yinyin Yuan, Mikko I Kettunen, Sarah N Dawson, Daniel Scoffings, Holly C Canuto, Sarah L Vowler, Heide Kirschenlohr, Michael P Hobson, Florian Markowetz, Sarah Jefferies, Kevin M Brindle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5435159?pdf=render