Bidirectional plasticity of GABAergic tonic inhibition in hippocampal somatostatin- and parvalbumin-containing interneurons

Bidirectional plasticity of GABAergic tonic inhibition in hippocampal somatostatin- and parvalbumin-containing interneurons

GABAA receptors present in extrasynaptic areas mediate tonic inhibition in hippocampal neurons regulating the performance of neural networks. In this study, we investigated the effect of NMDA-induced plasticity on tonic inhibition in somatostatin- and parvalbumin-containing interneurons. Using pharm...

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Bibliographic Details
Main Authors: Marcin Wyroślak, Grzegorz Dobrzański, Jerzy W. Mozrzymas
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
GABA
tonic inhibition
hippocampus
interneurons
plasticity
extrasynaptic receptors
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1193383/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2023.1193383/full

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