The roles of sclerostin and irisin on bone and muscle of orchiectomized rats

Abstract Background The reduction in androgen level gives rise to a decrease in bone mineral density (BMD) and muscle strength, but the exact mechanisms are unclear. We investigated the roles of novel cytokines of sclerostin and irisin on bone and muscle of orchiectomized rats. Methods Twenty 3-mont...

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Bibliographic Details
Main Authors: Bing-na Zhou, Qian Zhang, Xiao-yun Lin, Jing Hu, Di-chen Zhao, Yan Jiang, Xiao-ping Xing, Mei Li
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Musculoskeletal Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12891-022-05982-7