Transplantation of bone marrow-derived mononuclear cells improves mechanical hyperalgesia, cold allodynia and nerve function in diabetic neuropathy.

Relief from painful diabetic neuropathy is an important clinical issue. We have previously shown that the transplantation of cultured endothelial progenitor cells or mesenchymal stem cells ameliorated diabetic neuropathy in rats. In this study, we investigated whether transplantation of freshly isol...

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Bibliographic Details
Main Authors: Keiko Naruse, Jun Sato, Megumi Funakubo, Masaki Hata, Nobuhisa Nakamura, Yasuko Kobayashi, Hideki Kamiya, Taiga Shibata, Masaki Kondo, Tatsuhito Himeno, Tatsuaki Matsubara, Yutaka Oiso, Jiro Nakamura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3220696?pdf=render