Highly Efficient Purification of Recombinant VSV-∆G-Spike Vaccine against SARS-CoV-2 by Flow-Through Chromatography

Highly Efficient Purification of Recombinant VSV-∆G-Spike Vaccine against SARS-CoV-2 by Flow-Through Chromatography

This study reports a highly efficient, rapid one-step purification process for the production of the recombinant vesicular stomatitis virus-based vaccine, rVSV-∆G-spike (rVSV-S), recently developed by the Israel Institute for Biological Research (IIBR) for the prevention of COVID-19. Several purific...

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Bibliographic Details
Main Authors: Elad Lerer, Ziv Oren, Yaron Kafri, Yaakov Adar, Einat Toister, Lilach Cherry, Edith Lupu, Arik Monash, Rona Levy, Eyal Dor, Eyal Epstein, Lilach Levin, Meni Girshengorn, Niva Natan, Ran Zichel, Arik Makovitzki
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:BioTech
Subjects:
rVSV
SARS-CoV-2
downstream process
chromatography
membrane adsorbers
Online Access:https://www.mdpi.com/2673-6284/10/4/22

Internet

https://www.mdpi.com/2673-6284/10/4/22

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