Myomedin replicas of gp120 V3 loop glycan epitopes recognized by PGT121 and PGT126 antibodies as non-cognate antigens for stimulation of HIV-1 broadly neutralizing antibodies
IntroductionImprinting broadly neutralizing antibody (bNAb) paratopes by shape complementary protein mimotopes represents a potential alternative for developing vaccine immunogens. This approach, designated as a Non-Cognate Ligand Strategy (NCLS), has recently been used for the identification of pro...
Auteurs principaux: | , , , , , , , , , , , , , |
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Format: | Article |
Langue: | English |
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Frontiers Media S.A.
2022-12-01
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Collection: | Frontiers in Immunology |
Sujets: | |
Accès en ligne: | https://www.frontiersin.org/articles/10.3389/fimmu.2022.1066361/full |