The spectrum of TP53 mutations in Rwandan patients with gastric cancer

The spectrum of TP53 mutations in Rwandan patients with gastric cancer

Abstract Background Gastric cancer is the sixth most frequently diagnosed cancer and third in causing cancer-related death globally. The most frequently mutated gene in human cancers is TP53, which plays a pivotal role in cancer initiation and progression. In Africa, particularly in Rwanda, data on...

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Bibliographic Details
Main Authors: Augustin Nzitakera, Jean Bosco Surwumwe, Ella Larissa Ndoricyimpaye, Schifra Uwamungu, Delphine Uwamariya, Felix Manirakiza, Marie Claire Ndayisaba, Gervais Ntakirutimana, Benoit Seminega, Vincent Dusabejambo, Eric Rutaganda, Placide Kamali, François Ngabonziza, Rei Ishikawa, Belson Rugwizangoga, Yuji Iwashita, Hidetaka Yamada, Kimio Yoshimura, Haruhiko Sugimura, Kazuya Shinmura
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Genes and Environment
Subjects:
TP53
Mutation spectrum
Mutation pattern
Genetic analysis
Gastric cancer
Rwanda
Online Access:https://doi.org/10.1186/s41021-024-00302-y

Internet

https://doi.org/10.1186/s41021-024-00302-y

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