Tgf-beta induced Erk phosphorylation of smad linker region regulates smad signaling.

The Transforming Growth Factor-Beta (TGF-β) family is involved in regulating a variety of cellular processes such as apoptosis, differentiation, and proliferation. TGF-β binding to a Serine/Threonine kinase receptor complex causes the recruitment and subsequent activation of transcription factors kn...

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Bibliographic Details
Main Authors: Chris Hough, Maria Radu, Jules J E Doré
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3412844?pdf=render