Model-based simulation and prediction of an antiviral strategy against influenza A infection.

There is a strong need to develop novel strategies in using antiviral agents to efficiently treat influenza infections. Thus, we constructed a rule-based mathematical model that reflects the complicated interactions of the host immunity and viral life cycle and analyzed the key controlling steps of...

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Bibliographic Details
Main Authors: Kye-Yeon Hur, Joon-Young Moon, Seung-Hwan Kim, Joo-Yeon Yoo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3706530?pdf=render