Generation of iPSC-Derived Human Peripheral Sensory Neurons Releasing Substance P Elicited by TRPV1 Agonists

Generation of iPSC-Derived Human Peripheral Sensory Neurons Releasing Substance P Elicited by TRPV1 Agonists

Neural crest stem cells (NCPCs) have been shown to differentiate into various cell types and tissues during embryonic development, including sensory neurons. The few studies addressing the generation of NCPCs and peripheral sensory neurons (PSNs) from human induced pluripotent stem cells (hiPSCs), g...

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Bibliographic Details
Main Authors: Marília Z. P. Guimarães, Rodrigo De Vecchi, Gabriela Vitória, Jaroslaw K. Sochacki, Bruna S. Paulsen, Igor Lima, Felipe Rodrigues da Silva, Rodrigo F. M. da Costa, Newton G. Castro, Lionel Breton, Stevens K. Rehen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Molecular Neuroscience
Subjects:
human induced pluripotent stem cells (hiPSCs)
NCPC
TRPV1
sensory neurons
preclinical
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00277/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2018.00277/full

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