Assessing the Influence of Propylthiouracil and Phenytoin on the Metabolomes of the Thyroid, Liver, and Plasma in Rats

Assessing the Influence of Propylthiouracil and Phenytoin on the Metabolomes of the Thyroid, Liver, and Plasma in Rats

The thyroid hormones (THs) regulate various physiological mechanisms in mammals, such as cellular metabolism, cell structure, and membrane transport. The therapeutic drugs propylthiouracil (PTU) and phenytoin are known to induce hypothyroidism and decrease blood thyroid hormone levels. To analyze th...

Full description

Bibliographic Details
Main Authors: Zhipeng Wang, Sven-Bastiaan Haange, Volker Haake, Maike Huisinga, Hennicke Kamp, Roland Buesen, Kristin Schubert, Sebastian Canzler, Jörg Hackermüller, Ulrike Rolle-Kampczyk, Martin von Bergen
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Metabolites
Subjects:
thyroid hormones
propylthiouracil
phenytoin
metabolomics
hypothyroidism
Online Access:https://www.mdpi.com/2218-1989/13/7/847

Internet

https://www.mdpi.com/2218-1989/13/7/847

Similar Items