The integrated stress response effector GADD34 is repurposed by neurons to promote stimulus-induced translation

Summary: Neuronal protein synthesis is required for long-lasting plasticity and long-term memory consolidation. Dephosphorylation of eukaryotic initiation factor 2α is one of the key translational control events that is required to increase de novo protein synthesis that underlies long-lasting plast...

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Bibliographic Details
Main Authors: Mauricio M. Oliveira, Muhaned Mohamed, Megan K. Elder, Keylin Banegas-Morales, Maggie Mamcarz, Emily H. Lu, Ela A.N. Golhan, Nishika Navrange, Snehajyoti Chatterjee, Ted Abel, Eric Klann
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723016819