The Pathological Mechanisms of Hearing Loss Caused by <i>KCNQ1</i> and <i>KCNQ4</i> Variants

The Pathological Mechanisms of Hearing Loss Caused by <i>KCNQ1</i> and <i>KCNQ4</i> Variants

Deafness-associated genes <i>KCNQ1</i> (also associated with heart diseases) and <i>KCNQ4</i> (only associated with hearing loss) encode the homotetrameric voltage-gated potassium ion channels Kv7.1 and Kv7.4, respectively. To date, over 700 <i>KCNQ1</i> and over...

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Bibliographic Details
Main Author: Kazuaki Homma
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomedicines
Subjects:
<i>KCNQ1</i>
<i>KCNQ4</i>
Kv7.1
Kv7.4
hearing loss
DFNA2A
Online Access:https://www.mdpi.com/2227-9059/10/9/2254

Internet

https://www.mdpi.com/2227-9059/10/9/2254

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