Histology-informed multiscale modeling of human brain white matter

Abstract In this study, we propose a novel micromechanical model for the brain white matter, which is described as a heterogeneous material with a complex network of axon fibers embedded in a soft ground matrix. We developed this model in the framework of RVE-based multiscale theories in combination...

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Bibliographic Details
Main Authors: Saeideh Saeidi, Manuel P. Kainz, Misael Dalbosco, Michele Terzano, Gerhard A. Holzapfel
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-46600-3