Twenty-four hour rhythmicity in mitochondrial network connectivity and mitochondrial respiration; a study in human skeletal muscle biopsies of young lean and older individuals with obesity

Twenty-four hour rhythmicity in mitochondrial network connectivity and mitochondrial respiration; a study in human skeletal muscle biopsies of young lean and older individuals with obesity

Objective: Mitochondrial network dynamics may play role in metabolic homeostasis. Whether mitochondrial network dynamics are involved in adaptations to day–night fluctuations in energy supply and demand is unclear. Here we visualized and quantified the mitochondrial network morphology in human skele...

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Bibliographic Details
Main Authors: Anne Gemmink, Sabine Daemen, Jakob Wefers, Jan Hansen, Dirk van Moorsel, Puji Astuti, Johanna A. Jorgensen, Esther Kornips, Gert Schaart, Joris Hoeks, Patrick Schrauwen, Matthijs K.C. Hesselink
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Molecular Metabolism
Subjects:
Day-night rhythm
Mitochondrial network integrity
Skeletal muscle
Mitochondrial function
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877823000613

Internet

http://www.sciencedirect.com/science/article/pii/S2212877823000613

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