Purinergic P2X7 receptor expression increases in leukocytes from intra-abdominal septic patients

Purinergic P2X7 receptor expression increases in leukocytes from intra-abdominal septic patients

Inflammation is a tightly coordinated response of the host immune system to bacterial and viral infections, triggered by the production of inflammatory cytokines. Sepsis is defined as a systemic inflammatory response followed by immunosuppression of the host and organ dysfunction. This imbalance of...

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Bibliographic Details
Main Authors: Helios Martínez-Banaclocha, Carlos García-Palenciano, Laura Martínez-Alarcón, Joaquín Amores-Iniesta, Fátima Martín-Sánchez, Giovanni A. Ercole, Ada González-Lisorge, José Fernández-Pacheco, Piedad Martínez-Gil, Julio Padilla-Rodríguez, Alberto Baroja-Mazo, Pablo Pelegrín, Juan José Martínez-García
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
sepsis
inflammation
P2X7 receptor
purinergic signaling
danger signals
leukocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1297249/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1297249/full

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