RNA interference of GADD153 protects photoreceptors from endoplasmic reticulum stress-mediated apoptosis after retinal detachment.

RNA interference of GADD153 protects photoreceptors from endoplasmic reticulum stress-mediated apoptosis after retinal detachment.

BACKGROUND: Apoptosis of photoreceptors plays a critical role in the vision loss caused by retinal detachment (RD). Pharmacologic inhibition of photoreceptor cell death may prevent RD. This study investigated the role of GADD153 that participates in endoplasmic reticulum (ER) stress-mediated apoptos...

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Bibliographic Details
Main Authors: Hong Zhu, Jin Qian, Wenqiu Wang, Quan Yan, Ying Xu, Yuan Jiang, Lei Zhang, Fengqing Lu, Weiting Hu, Xi Zhang, Fenghua Wang, Xiaodong Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3612068?pdf=render

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http://europepmc.org/articles/PMC3612068?pdf=render

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