The Role of Hepatitis C Virus NS5A Region Mutation and SNP IL-28B of Host to Support Successful Pegylated Interferon and Ribavirin Treatment in Patients with HCV-HIV Coinfection: A Prospective Cohort Study

The Role of Hepatitis C Virus NS5A Region Mutation and SNP IL-28B of Host to Support Successful Pegylated Interferon and Ribavirin Treatment in Patients with HCV-HIV Coinfection: A Prospective Cohort Study

Background: HIV infection in HCV-infected patients accelerates disease progression and reduces the success rate of Peg-IFN/RBV treatment. HCV mutation in NS5A-ISDR/PKR-BD region improved the outcome in HCV monoinfection treated with Peg-IFN/RBV. SNP-IL28B polymorphism is predicted to have an effect...

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Bibliographic Details
Main Authors: Juferdy Kurniawan, Rino A Gani, Samsuridjal Djauzi, Fera Ibrahim, Kuntjoro Harimurti, nafrialdi nafrialdi, Suzanna Imannuel
Format: Article
Language:English
Published: Interna Publishing 2019-08-01
Series:Acta Medica Indonesiana
Subjects:
NS5A-ISDR/PKR-BD
SNP IL-28B
HCV-HIV coinfection
nonneutral mutation
SVR
Online Access:http://actamedindones.org/index.php/ijim/article/view/1061

Internet

http://actamedindones.org/index.php/ijim/article/view/1061

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