Identification of a novel fully human anti-toxic shock syndrome toxin (TSST)-1 single-chain variable fragment antibody averting TSST-1-induced mitogenesis and cytokine secretion
Abstract Background Staphylococcal superantigens are virulence factors that help the pathogen escape the immune system and develop an infection. Toxic shock syndrome toxin (TSST)-1 is one of the most studied superantigens whose role in toxic shock syndrome and some particular disorders have been dem...
Main Authors: | Mahdieh Soezi, Somayeh Piri-Gavgani, Mostafa Ghanei, Mir Davood Omrani, Behnoush Soltanmohammadi, Kamran Pooshang Bagheri, Reza Ahangari Cohan, Farzam Vaziri, Seyed Davar Siadat, Abolfazl Fateh, Shohreh Khatami, Masoumeh Azizi, Fatemeh Rahimi-Jamnani |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-10-01
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Series: | BMC Biotechnology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12896-022-00760-8 |
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