Enzymatic Synthesis of New Acetoacetate–Ursodeoxycholic Acid Hybrids as Potential Therapeutic Agents and Useful Synthetic Scaffolds as Well

Enzymatic Synthesis of New Acetoacetate–Ursodeoxycholic Acid Hybrids as Potential Therapeutic Agents and Useful Synthetic Scaffolds as Well

Ursodeoxycholic acid (UDCA) and acetoacetate are natural compounds present in the human intestine and blood, respectively. A number of studies highlighted that besides their well-known primary biological roles, both compounds possess the ability to influence a variety of cellular processes involved...

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Bibliographic Details
Main Authors: Valentina Venturi, Elena Marchesi, Daniela Perrone, Valentina Costa, Martina Catani, Simona Aprile, Lindomar Alberto Lerin, Federico Zappaterra, Pier Paolo Giovannini, Lorenzo Preti
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Molecules
Subjects:
biocatalysis
ursodeoxycholic acid
ketone bodies
acetoacetate
lipase
hybrid compounds
Online Access:https://www.mdpi.com/1420-3049/29/6/1305

Internet

https://www.mdpi.com/1420-3049/29/6/1305

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