Association of rs4680 COMT, rs6280 DRD3, and rs7322347 5HT2A With Clinical Features of Youth-Onset Schizophrenia

Association of rs4680 COMT, rs6280 DRD3, and rs7322347 5HT2A With Clinical Features of Youth-Onset Schizophrenia

We investigated the associations of rs4680 COMT, rs6280 DRD3, and rs7322347 5HT2A with youth-onset schizophrenia in the Russian population in a case–control study, and the role of the genotype in the severity of clinical features. The association between rs7322347 and schizophrenia (p = 0.0001) is d...

Full description

Bibliographic Details
Main Authors: Anna Morozova, Yana Zorkina, Konstantin Pavlov, Olga Pavlova, Zinaida Storozheva, Eugene Zubkov, Natalia Zakharova, Olga Karpenko, Alexander Reznik, Vladimir Chekhonin, Georgiy Kostyuk
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Psychiatry
Subjects:
single-nucleotide polymorphism
schizophrenia
youth-onset
5-hydroxytryptamine 2A receptors
dopamine receptor D3
catechol-O-methyltransferase
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2019.00830/full

Internet

https://www.frontiersin.org/article/10.3389/fpsyt.2019.00830/full

Similar Items