Columbianadin attenuates doxorubicin-induced cardiac injury, oxidative stress, and apoptosis via Sirt1/FOXO1 signaling pathway

Columbianadin attenuates doxorubicin-induced cardiac injury, oxidative stress, and apoptosis via Sirt1/FOXO1 signaling pathway

ABSTRACT Purpose: Oxidative stress and apoptosis contribute to the pathological basis of doxorubicin (DOX)-induced cardiotoxicity. Columbianadin (CBN) is one of the main bioactive constituents isolated from the root of Angelica pubescens. Herein, we intended to explore the potential role and molecu...

Full description

Bibliographic Details
Main Authors: Bo Peng, Li Rao, Jiaolong Yang, Xiaowei Ku, Bin Kong, Wei Shuai, He Huang
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2023-06-01
Series:Acta Cirúrgica Brasileira
Subjects:
Doxorubicin
Cardiotoxicity
Oxidative Stress
Apoptosis
Sirtuin 1
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502023000100217&tlng=en

Similar Items

Similar Items