DREADD-mediated amygdala activation is sufficient to induce anxiety-like responses in young nonhuman primates

DREADD-mediated amygdala activation is sufficient to induce anxiety-like responses in young nonhuman primates

Anxiety disorders are among the most prevalent psychiatric disorders, with symptoms often beginning early in life. To model the pathophysiology of human pathological anxiety, we utilized Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) in a nonhuman primate model of anxious tempe...

Full description

Bibliographic Details
Main Authors: Sascha A.L. Mueller, Jonathan A. Oler, Patrick H. Roseboom, Nakul Aggarwal, Margaux M. Kenwood, Marissa K. Riedel, Victoria R. Elam, Miles E. Olsen, Alexandra H. DiFilippo, Bradley T. Christian, Xing Hu, Adriana Galvan, Matthew A. Boehm, Michael Michaelides, Ned H. Kalin
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Current Research in Neurobiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2665945X23000396

Internet

http://www.sciencedirect.com/science/article/pii/S2665945X23000396

Similar Items