Modulation of the mTOR Pathway by Curcumin in the Heart of Septic Mice

mTOR is a signaling pathway involved in cell survival, cell stress response, and protein synthesis that may be a key point in sepsis-induced cardiac dysfunction. Curcumin has been reported in vitro as an mTOR inhibitor compound; however, there are no studies demonstrating this effect in experimental...

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Bibliographic Details
Main Authors: Bruna A. C. Rattis, Henrique L. Piva, Andressa Duarte, Frederico G. F. L. R. Gomes, Janaína R. Lellis, Danilo F. Soave, Simone G. Ramos, Antonio C. Tedesco, Mara R. N. Celes
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/14/11/2277