Scalable Production of HPV16 L1 Protein and VLPs from Tobacco Leaves.

Cervical cancer is the most common malignancy among women particularly in developing countries, with human papillomavirus (HPV) 16 causing 50% of invasive cervical cancers. A plant-based HPV vaccine is an alternative to the currently available virus-like particle (VLP) vaccines, and would be much le...

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Bibliographic Details
Main Authors: Maryam Zahin, Joongho Joh, Sujita Khanal, Adam Husk, Hugh Mason, Heribert Warzecha, Shin-Je Ghim, Donald M Miller, Nobuyuki Matoba, Alfred Bennett Jenson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4982596?pdf=render