Characterizing Epitope Binding Regions of Entire Antibody Panels by Combining Experimental and Computational Analysis of Antibody: Antigen Binding Competition

Characterizing Epitope Binding Regions of Entire Antibody Panels by Combining Experimental and Computational Analysis of Antibody: Antigen Binding Competition

Vaccines and immunotherapies depend on the ability of antibodies to sensitively and specifically recognize particular antigens and specific epitopes on those antigens. As such, detailed characterization of antibody–antigen binding provides important information to guide development. Due to the time...

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Bibliographic Details
Main Authors: Benjamin D. Brooks, Adam Closmore, Juechen Yang, Michael Holland, Tina Cairns, Gary H. Cohen, Chris Bailey-Kellogg
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Molecules
Subjects:
epitope binning
epitope mapping
epitope prediction
antibody:antigen interactions
protein docking
glycoprotein D (gD)
Online Access:https://www.mdpi.com/1420-3049/25/16/3659

Internet

https://www.mdpi.com/1420-3049/25/16/3659

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