Kupffer Cells Sense Free Fatty Acids and Regulate Hepatic Lipid Metabolism in High-Fat Diet and Inflammation

Kupffer Cells Sense Free Fatty Acids and Regulate Hepatic Lipid Metabolism in High-Fat Diet and Inflammation

A high fat Western-style diet leads to hepatic steatosis that can progress to steatohepatitis and ultimately cirrhosis or liver cancer. The mechanism that leads to the development of steatosis upon nutritional overload is complex and only partially understood. Using click chemistry-based metabolic t...

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Bibliographic Details
Main Authors: Kira L. Diehl, Julia Vorac, Kristina Hofmann, Philippa Meiser, Iris Unterweger, Lars Kuerschner, Heike Weighardt, Irmgard Förster, Christoph Thiele
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cells
Subjects:
non-alcoholic fatty liver disease
nutrition/lipids
metabolic disease
lipids/chemistry
Online Access:https://www.mdpi.com/2073-4409/9/10/2258

Internet

https://www.mdpi.com/2073-4409/9/10/2258

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