A Chemical Recipe for Generation of Clinical-Grade Striatal Neurons from hESCs

A Chemical Recipe for Generation of Clinical-Grade Striatal Neurons from hESCs

Summary: Differentiation of human pluripotent stem cells (hPSCs) into striatal medium spiny neurons (MSNs) promises a cell-based therapy for Huntington's disease. However, clinical-grade MSNs remain unavailable. Here, we developed a chemical recipe named XLSBA to generate clinical-grade MSNs fr...

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Bibliographic Details
Main Authors: Menghua Wu, Da Zhang, Chunying Bi, Tingwei Mi, Wenliang Zhu, Longkuo Xia, Zhaoqian Teng, Baoyang Hu, Yihui Wu
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118303266

Internet

http://www.sciencedirect.com/science/article/pii/S2213671118303266

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