Bioengineered Human Stromal Lenticule for Recombinant Human Nerve Growth Factor Release: A Potential Biocompatible Ocular Drug Delivery System

Bioengineered Human Stromal Lenticule for Recombinant Human Nerve Growth Factor Release: A Potential Biocompatible Ocular Drug Delivery System

Small incision lenticule extraction (SMILE), is a surgical procedure for the myopia correction, during which a corneal stromal lenticule is extracted. Given that we have previously demonstrated how this discarded tissue could be repurposed as a bio-scaffold for stromal engineering, this study aimed...

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Bibliographic Details
Main Authors: Leonardo Mastropasqua, Mario Nubile, Giuseppina Acerra, Nicola Detta, Letizia Pelusi, Manuela Lanzini, Simone Mattioli, Manuela Santalucia, Laura Pietrangelo, Marcello Allegretti, Harminder S. Dua, Jodhbir S. Mehta, Assunta Pandolfi, Domitilla Mandatori
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
decellularization
drug delivery
microparticles
nerve growth factor
scaffold
smile
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.887414/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.887414/full

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