A simple null model for inferences from network enrichment analysis.

A prevailing technique to infer function from lists of identifications, from molecular biological high-throughput experiments, is over-representation analysis, where the identifications are compared to predefined sets of related genes often referred to as pathways. As at least some pathways are know...

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Bibliographic Details
Main Authors: Gustavo S Jeuken, Lukas Käll
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6226187?pdf=render