Antidepressant-Like Properties of Intrastriatal Botulinum Neurotoxin-A Injection in a Unilateral 6-OHDA Rat Model of Parkinson’s Disease

Parkinson’s patients often suffer from depression and anxiety, for which there are no optimal treatments. Hemiparkinsonian (hemi-PD) rats were used to test whether intrastriatal Botulinum neurotoxin-A (BoNT-A) application could also have antidepressant-like properties in addition to the known improv...

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Bibliographic Details
Main Authors: Veronica Antipova, Carsten Holzmann, Alexander Hawlitschka, Martin Witt, Andreas Wree
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/13/7/505