Effect and mechanism of CyPA in radiosensitization of lung adenocarcinoma using CRISPR/Cas9 technology

Objective: To explore the role of cyclophilin A (CyPA) in sensitization of lung adenocarcinoma to radiotherapy using CRISPR/Cas9 technology. Methods: A CyPA knockout human lung adenocarcinoma cell line H1975 was established by CRISPR/Cas9 technology. Groups included a control group (wildtype), CyPA...

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Bibliographic Details
Main Authors: Jinkun Ma, Lin Xu, Jinchang Huang, Qiaoli Zhang, Yuqin Qiu, Xuewei Qi, Lina Wang, Yuchan Cao, Zeyu Liu, Shiyun Liu
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Journal of Traditional Chinese Medical Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S2095754820300065