Evolutionarily Ancient Caspase-9 Sensitizes Immune Effector Coelomocytes to Cadmium-Induced Cell Death in the Sea Cucumber, Holothuria leucospilota

Evolutionarily Ancient Caspase-9 Sensitizes Immune Effector Coelomocytes to Cadmium-Induced Cell Death in the Sea Cucumber, Holothuria leucospilota

Heavy-metal pollution has increasingly jeopardized the habitats of marine organisms including the sea cucumber, a seafloor scavenger vital to seawater bio-decontamination, ocean de-acidification and coral-reef protection. Normal physiology including immune functions of sea cucumbers is toxicological...

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Bibliographic Details
Main Authors: Xiaomin Li, Ting Chen, Xiaofen Wu, Zhuobo Li, Xin Zhang, Xiao Jiang, Peng Luo, Chaoqun Hu, Nai-Kei Wong, Chunhua Ren
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
caspase-9
cadmium
reactive oxygen/nitrogen species (ROS/RNS)
Holothuria leucospilota
invertebrate cell death
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.927880/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.927880/full

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