Peroxisome Proliferator-Activated Receptor gamma negatively regulates liver regeneration after partial hepatectomy via the HGF/c-Met/ERK1/2 pathways

Peroxisome Proliferator-Activated Receptor gamma negatively regulates liver regeneration after partial hepatectomy via the HGF/c-Met/ERK1/2 pathways

Abstract Peroxisome Proliferator-Activated Receptor gamma (PPARγ) is a nuclear receptor demonstrated to play an important role in various biological processes. The aim of this study was to determine the effect of PPARγ on liver regeneration upon partial hepatectomy (PH) in mice. Mice were subjected...

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Bibliographic Details
Main Authors: Zhangjun Cheng, Lei Liu, Xue-Jun Zhang, Miao Lu, Yang Wang, Volker Assfalg, Melanie Laschinger, Guido von Figura, Yoshiaki Sunami, Christoph W. Michalski, Jörg Kleeff, Helmut Friess, Daniel Hartmann, Norbert Hüser
Format: Article
Language:English
Published: Nature Portfolio 2018-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-30426-5

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https://doi.org/10.1038/s41598-018-30426-5

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