The Generation of an Artificial ATP Deficit Triggers Antibiotic Production in <i>Streptomyces lividans</i>

The Generation of an Artificial ATP Deficit Triggers Antibiotic Production in <i>Streptomyces lividans</i>

In most <i>Streptomyces</i> species, antibiotic production is triggered in a condition of phosphate limitation, a condition that is known to be correlated with a low intracellular ATP content compared to growth in a condition of phosphate proficiency. This observation suggests that a low...

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Bibliographic Details
Main Authors: Nicolas Seghezzi, Emmanuelle Darbon, Cécile Martel, Michelle David, Clara Lejeune, Catherine Esnault, Marie-Joelle Virolle
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Antibiotics
Subjects:
phosphate limitation
ATP deficit
oxidative phosphorylation
oxidative stress
ATPase
antibiotics
Online Access:https://www.mdpi.com/2079-6382/11/9/1157

Internet

https://www.mdpi.com/2079-6382/11/9/1157

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