Synthesis and Structure Activity Relationship of Some Indole Derivatives as Potential Anti-inflammatory Agents

A series of fused pyrroles were synthesized and tested for their in vivo anti-inflammatory activity. Among 14 examined derivatives, 5 derivatives (1b–e,g and 5b), showed a promising anti-inflammatory activity equivalent to reference anti-inflammatory drugs (indomethacin and ibuprofen). A molecular d...

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Bibliographic Details
Main Authors: Samar S. Fatahala, Mohammed A. Khedr, Mossad S. Mohamed
Format: Article
Language:English
Published: Slovenian Chemical Society 2017-12-01
Series:Acta Chimica Slovenica
Subjects:
Online Access:https://journals.matheo.si/index.php/ACSi/article/view/3481