Profiling the antidepressant properties of phenyl piperidine derivatives as inhibitors of serotonin transporter (SERT) via cheminformatics modeling, molecular docking and ADMET predictions.
The inhibition of serotonin transporter (SERT) has been considered to be a good target for the treatment of mood disorders (depression). The present study employed cheminformatics modeling, molecular docking analysis and ADMET predictions approaches on some Phenyl piperidine derivatives reported as...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-09-01
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| Series: | Scientific African |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468227620302556 |