Preoperative sequential short-course radiation therapy and FOLFOX chemotherapy versus long-course chemoradiotherapy for locally advanced rectal cancer: a multicenter, randomized controlled trial (SOLAR trial)

Preoperative sequential short-course radiation therapy and FOLFOX chemotherapy versus long-course chemoradiotherapy for locally advanced rectal cancer: a multicenter, randomized controlled trial (SOLAR trial)

Abstract Background Preoperative (chemo)radiotherapy has been widely used as an effective treatment for locally advanced rectal cancer (LARC), leading to a significant reduction in pelvic recurrence rates. Because early administration of intensive chemotherapy for LARC has more advantages than adjuv...

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Bibliographic Details
Main Authors: Min Kyu Kang, Soo Yeun Park, Jun Seok Park, Hye Jin Kim, Jong Gwang Kim, Byung Woog Kang, Jin Ho Baek, Seung Hyun Cho, An Na Seo, Duck-Woo Kim, Jin Kim, Se Jin Baek, Ji Hoon Kim, Ji Yeon Kim, Gi Won Ha, Eun Jung Park, In Ja Park, Chang Hyun Kim, Hyun Kang, Gyu-Seog Choi
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Cancer
Subjects:
Rectal neoplasm
Neoadjuvant radiotherapy
Short-course radiation
Consolidation chemotherapy
Disease-free survival
Randomized controlled phase II trial
Online Access:https://doi.org/10.1186/s12885-023-11363-7

Internet

https://doi.org/10.1186/s12885-023-11363-7

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