Genome‐wide analysis of DNA methylation identifies the apoptosis‐related gene UQCRH as a tumor suppressor in renal cancer

DNA hypermethylation is frequently observed in clear cell renal cell carcinoma (ccRCC) and correlates with poor clinical outcomes. However, the detailed function of DNA hypermethylation in ccRCC has not been fully uncovered. Here, we show the role of DNA methylation in ccRCC progression through the...

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Bibliographic Details
Main Authors: Kosuke Miyakuni, Jun Nishida, Daizo Koinuma, Genta Nagae, Hiroyuki Aburatani, Kohei Miyazono, Shogo Ehata
Format: Article
Language:English
Published: Wiley 2022-02-01
Series:Molecular Oncology
Subjects:
Online Access:https://doi.org/10.1002/1878-0261.13040