Chronic consumption of a hypercaloric diet increases neuroinflammation and brain senescence, promoting cognitive decline in middle-aged female Wistar rats

Chronic consumption of a hypercaloric diet increases neuroinflammation and brain senescence, promoting cognitive decline in middle-aged female Wistar rats

Being overweight and obesity are world health problems, with a higher prevalence in women, defined as abnormal or excessive fat accumulation that increases the risk of chronic diseases. Excess energy leads to adipose expansion, generating hypertrophic adipocytes that produce various pro-inflammatory...

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Bibliographic Details
Main Authors: Verónica Salas-Venegas, Roberto Santín-Márquez, Ricardo Jair Ramírez-Carreto, Yesica María Rodríguez-Cortés, Agustina Cano-Martínez, Armando Luna-López, Anahí Chavarría, Mina Konigsberg, Norma Edith López-Díazguerrero
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
obesity
female
neuroinflammation
senescence
cognitive deterioration
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1162747/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2023.1162747/full

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