Effects of trastuzumab and trastuzumab emtansine on corrected QT interval and left ventricular ejection fraction in patients with metastatic (HER2+) breast cancer

Effects of trastuzumab and trastuzumab emtansine on corrected QT interval and left ventricular ejection fraction in patients with metastatic (HER2+) breast cancer

Abstract Background Trastuzumab and trastuzumab emtansine are specific antibody and antibody–drug conjugates used in the treatment of human epidermal growth factor receptor 2 (HER2) positive metastatic breast cancer. The aim of this study was to test their effect on the QTc interval duration and lef...

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Bibliographic Details
Main Authors: Rea Levicki, Martina Lovrić Benčić, Irena Ivanac Vranešić, Lada Bradić, Marta Begovac, Juraj Jug, Natalija Dedić Plavetić
Format: Article
Language:English
Published: SpringerOpen 2023-02-01
Series:The Egyptian Heart Journal
Subjects:
Trastuzumab
Cardiotoxicity
Breast cancer
Online Access:https://doi.org/10.1186/s43044-023-00331-y

Internet

https://doi.org/10.1186/s43044-023-00331-y

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