Characterization of Cell Death Induced by Imine Analogs of Trans-Resveratrol: Induction of Mitochondrial Dysfunction and Overproduction of Reactive Oxygen Species Leading to, or Not, Apoptosis without the Increase in the S-Phase of the Cell Cycle

Characterization of Cell Death Induced by Imine Analogs of Trans-Resveratrol: Induction of Mitochondrial Dysfunction and Overproduction of Reactive Oxygen Species Leading to, or Not, Apoptosis without the Increase in the S-Phase of the Cell Cycle

<i>Trans</i>-resveratrol (RSV) is a non-flavonoid polyphenol (stilbene) with numerous biological activities, such as anti-tumor activities. However, RSV is rapidly metabolized, which limits its therapeutic use. The availability of RSV analogues with similar activities for use in vivo is...

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Bibliographic Details
Main Authors: Mohamed Ksila, Imen Ghzaiel, Vivien Pires, Taoufik Ghrairi, Olfa Masmoudi-Kouki, Norbert Latruffe, Dominique Vervandier-Fasseur, Anne Vejux, Gérard Lizard
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Molecules
Subjects:
apoptosis
aza-stilbenes
cell death
cell cycle
flow cytometry
imine analogs of <i>trans</i>-resveratrol
Online Access:https://www.mdpi.com/1420-3049/28/7/3178

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https://www.mdpi.com/1420-3049/28/7/3178

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