Getting to the heart of an unusual kinetochore

The Mis12 complex forms the central scaffold of the kinetochore and serves to bridge the chromatin and microtubule-binding activities of the inner and outer layers, respectively. Two recent studies provide new structural insights into the formation of this complex, and highlight some intriguing adap...

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Bibliographic Details
Main Author: Martin R. Singleton
Format: Article
Language:English
Published: The Royal Society 2016-01-01
Series:Open Biology
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.160040