The C-terminal region of Net1 is an activator of RNA polymerase I transcription with conserved features from yeast to human.

The C-terminal region of Net1 is an activator of RNA polymerase I transcription with conserved features from yeast to human.

RNA polymerase I (Pol I) synthesizes ribosomal RNA (rRNA) in all eukaryotes, accounting for the major part of transcriptional activity in proliferating cells. Although basal Pol I transcription factors have been characterized in diverse organisms, the molecular basis of the robust rRNA production in...

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Bibliographic Details
Main Authors: Katharina Hannig, Virginia Babl, Kristin Hergert, Andreas Maier, Michael Pilsl, Christopher Schächner, Ulrike Stöckl, Philipp Milkereit, Herbert Tschochner, Wolfgang Seufert, Joachim Griesenbeck
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC6415870?pdf=render

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http://europepmc.org/articles/PMC6415870?pdf=render

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