Integration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort study

Integration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort study

Background: Understanding the heterogeneous genotypes and phenotypes of prostate cancer is fundamental to improving the way we treat this disease. As yet, there are no validated descriptions of prostate cancer subgroups derived from integrated genomics linked with clinical outcome. Methods: In a stu...

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Bibliographic Details
Main Authors: H. Ross-Adams, A.D. Lamb, M.J. Dunning, S. Halim, J. Lindberg, C.M. Massie, L.A. Egevad, R. Russell, A. Ramos-Montoya, S.L. Vowler, N.L. Sharma, J. Kay, H. Whitaker, J. Clark, R. Hurst, V.J. Gnanapragasam, N.C. Shah, A.Y. Warren, C.S. Cooper, A.G. Lynch, R. Stark, I.G. Mills, H. Grönberg, D.E. Neal
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:EBioMedicine
Subjects:
Prostate cancer
Risk stratification
Genomics
Prognosis
Gene signature
Biochemical relapse
Personalised medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415300712

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http://www.sciencedirect.com/science/article/pii/S2352396415300712

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