Supramolecular Protein-Polyelectrolyte Assembly at Near Physiological Conditions—Water Proton NMR, ITC, and DLS Study

Supramolecular Protein-Polyelectrolyte Assembly at Near Physiological Conditions—Water Proton NMR, ITC, and DLS Study

The in vivo potency of polyphosphazene immunoadjuvants is inherently linked to the ability of these ionic macromolecules to assemble with antigenic proteins in aqueous solutions and form physiologically stable supramolecular complexes. Therefore, in-depth knowledge of interactions in this biological...

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Bibliographic Details
Main Authors: Alexander Marin, Marc B. Taraban, Vanshika Patel, Y. Bruce Yu, Alexander K. Andrianov
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
protein–polyelectrolyte interactions
polyphosphazenes
supramolecular assembly
isothermal titration calorimetry
water proton transverse relaxation rate
dynamic light scattering
Online Access:https://www.mdpi.com/1420-3049/27/21/7424

Internet

https://www.mdpi.com/1420-3049/27/21/7424

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