Therapeutic Potential of Mesenchymal Stem Cell-Secreted Factors on Delay in Corneal Wound Healing by Nitrogen Mustard

Therapeutic Potential of Mesenchymal Stem Cell-Secreted Factors on Delay in Corneal Wound Healing by Nitrogen Mustard

Ocular surface exposure to nitrogen mustard (NM) leads to severe ocular toxicity which includes the separation of epithelial and stromal layers, loss of endothelial cells, cell death, and severe loss of tissue function. No definitive treatment for mustard gas-induced ocular surface disorders is curr...

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Bibliographic Details
Main Authors: Seungwon An, Xiang Shen, Khandaker Anwar, Mohammadjavad Ashraf, Hyungjo Lee, Raghuram Koganti, Mahmood Ghassemi, Ali R. Djalilian
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
nitrogen mustard
mesenchymal stem cell-conditioned media
corneal injury
apoptotic cell death
cellular ROS
delayed wound healing
Online Access:https://www.mdpi.com/1422-0067/23/19/11510

Internet

https://www.mdpi.com/1422-0067/23/19/11510

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