TUFT1 promotes metastasis and chemoresistance in triple negative breast cancer through the TUFT1/Rab5/Rac1 pathway

TUFT1 promotes metastasis and chemoresistance in triple negative breast cancer through the TUFT1/Rab5/Rac1 pathway

Abstract Background Triple negative breast cancer (TNBC) is a breast cancer (BC) subtype that is characterized by its strong invasion and a high risk of metastasis. However, the specific mechanisms underlying these phenotypes are unclear. TUFT1 plays an important role in BC and impacts the prolifera...

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Bibliographic Details
Main Authors: Weiguang Liu, Jianjun Han, Sufang Shi, Yuna Dai, Jianchao He
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Cancer Cell International
Subjects:
Triple negative breast cancer
TUFT1
Rab5
Metastasis
Chemoresistance
Prognosis
Online Access:http://link.springer.com/article/10.1186/s12935-019-0961-4

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http://link.springer.com/article/10.1186/s12935-019-0961-4

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